Search Unigenes:
Smed Unigene SMU15032988 : Cannot Determine

SMU15032988 is represented by 27 transcripts from 12 libraries.


Smed Unigenes are generated by clustering all available transcripts to generate a model, or Smed Unigene, representing all similar transcripts. The Smed Unigene may not accurately reflect each transcript due to biological processes such as alternative splicing.

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with ENSEMBL and SWISPROT proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms SpeciesSpecies or DBE-value
CAZ37317.2eukaryotic translation initiation factor 2c,putative [Schistosoma mansoni]NCBI-nr2e-158
ENSP00000220592argonaute RISC catalytic component 2H.sapiens1e-135
FBpp0086739Argonaute-1H.sapiens1e-134
F48F7.1aCaenorhabditis elegans Protein ALG-1, isoform a (alg-1) mRNA, complete cds.H.sapiens3e-127
AGO2_XENLAProtein argonaute-2 OS=Xenopus laevis GN=ago2 PE=2 SV=1Swissprot2e-135
SELECTED MOTIF SIMILARITIES
Comparison of cluster transcripts with INTERPRO. The alignments can suggest function of the cluster.

Identified MotifsDatabaseMax Score
PF02171.12|Piwi|Piwi domainPFAM8.8e-96
PF02170.17|PAZ|PAZ domainPFAM1.6e-17
Coiled-coilncoilsmotif found
TRANSCRIPTS
Amino acid translations of transcipts were clustered and used to generate a Smed Unigene. These transcripts are those that were clustered as well as other transcripts and sequences that have homology to the transcripts of the unigene cluster.

Transcript IDView Assembly AlignmentsTranscript Collection
GAKN01011665.1
TORONTO
comp41882_c1_seq1
SXLWT
comp67238_c0_seq2
ASXLREGEN
31356_c0s1
SRG12
31356_c0s2
SRG12
smedV4_2478_0_1
DD
smedV4_1194_0_1
DD
comp59317_c0_seq2
ASXLWT
c81582_g1_i1
SXLREGEN
c81582_g1_i2
SXLREGEN
Smed_1.0.05407
OX
Smed_1.0.01749
OX
Smed_1.0.20836
OX
comp80522_c0_seq2
ASXLSORT
comp80522_c0_seq1
ASXLSORT
comp80522_c0_seq3
ASXLSORT
smed000704
UNIQ
SMEDS2F2_00005078-RA_1_2525
UNIQ
sm_rc_90498
UNIQ
sm_90498
UNIQ
rc_smed000704
UNIQ
Contig34181
PN
Contig30967
PN
Contig35094
PN
Contig28851
PN
isotig19155
BERLIN
isotig02996
BERLIN
Associated Gene Ontology Terms
Gene Ontology terms are derived from the unigene transcript cluster compared to InterPro proteins. The GO terms can suggest function of the cluster.

GO:0000340
Name RNA 7-methylguanosine cap binding
Ontology Molecular function
Synonymn
  • exact: RNA m7G cap binding
Definition Interacting selectively and non-covalently with the 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.

GO:0000932
Name cytoplasmic mRNA processing body
Ontology Cellular component
Synonymn
  • exact: P body
  • exact: P-body
  • related: cytoplasmic foci
Definition A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci.

GO:0005845
Name mRNA cap binding complex
Ontology Cellular component
Synonymn
  • related: mRNA cap complex
Definition Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.

GO:0006355
Name regulation of transcription, DNA-templated
Ontology Biological process
Synonymn
  • alt_id: GO:0032583
  • alt_id: GO:0045449
  • alt_id: GO:0061019
  • broad: transcriptional control
  • exact: regulation of cellular transcription, DNA-dependent
  • exact: regulation of transcription, DNA-dependent
  • related: regulation of gene-specific transcription
Definition Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

GO:0016442
Name RISC complex
Ontology Cellular component
Synonymn
  • exact: RNA-induced silencing complex
Definition A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.

GO:0031047
Name gene silencing by RNA
Ontology Biological process
Synonymn
  • exact: RNA-mediated gene silencing
Definition Any process in which RNA molecules inactivate expression of target genes.

GO:0031054
Name pre-miRNA processing
Ontology Biological process
Synonymn
  • exact: pre-microRNA processing
Definition Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.

GO:0035068
Name micro-ribonucleoprotein complex
Ontology Cellular component
Synonymn
  • exact: miRNP complex
Definition A complex containing both protein and micro-RNA (miRNA) molecules. miRNAs are approximately 22 nucleotide noncoding RNAs derived from endogenous genes; they are processed from the stem of a longer hairpin like structure termed a pre-miRNA.

GO:0035197
Name siRNA binding
Ontology Molecular function
Synonymn
  • exact: small interfering RNA binding
Definition Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme.

GO:0035198
Name miRNA binding
Ontology Molecular function
Synonymn
  • exact: microRNA binding
Definition Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.

GO:0035278
Name negative regulation of translation involved in gene silencing by miRNA
Ontology Biological process
Synonymn
  • exact: down regulation of translation involved in gene silencing by miRNA
  • exact: down-regulation of translation involved in gene silencing by miRNA
  • exact: downregulation of translation involved in gene silencing by miRNA
  • exact: gene silencing by miRNA, negative regulation of translation
  • exact: negative regulation of translation involved in gene silencing by microRNA
  • narrow: inhibition of translation involved in gene silencing by miRNA
  • related: miRNA-mediated gene silencing, negative regulation of translation
Definition The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.

GO:0035279
Name mRNA cleavage involved in gene silencing by miRNA
Ontology Biological process
Synonymn
  • exact: gene silencing by miRNA, mRNA cleavage
  • exact: mRNA cleavage involved in gene silencing by microRNA
  • exact: miRNA-mediated gene silencing, mRNA cleavage
Definition The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically direct cleavage by base pairing with near-perfect complementarity to the target mRNA. Many plant miRNAs downregulate gene expression through this mechanism.

GO:0045947
Name negative regulation of translational initiation
Ontology Biological process
Synonymn
  • exact: down regulation of translational initiation
  • exact: down-regulation of translational initiation
  • exact: downregulation of translational initiation
  • narrow: inhibition of translational initiation
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.

GO:0046872
Name metal ion binding
Ontology Molecular function
Synonymn
  • exact: metal binding
  • narrow: heavy metal binding
Definition Interacting selectively and non-covalently with any metal ion.

GO:0060213
Name positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
Ontology Biological process
Synonymn
  • related: positive regulation of 3' to 5' mRNA deadenylation
  • related: positive regulation of mRNA deadenylation
  • related: positive regulation of nuclear mRNA poly(A) tail shortening
Definition Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.

GO:0070551
Name endoribonuclease activity, cleaving siRNA-paired mRNA
Ontology Molecular function
Synonymn
  • related: argonaute endoribonuclease activity
Definition Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.

GO:0090502
Name RNA phosphodiester bond hydrolysis, endonucleolytic
Ontology Biological process
Definition The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.

GO:1900153
Name positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Ontology Biological process
Synonymn
  • exact: positive regulation of deadenylation-dependent mRNA decay
  • exact: positive regulation of mRNA breakdown, deadenylation-dependent decay
  • exact: positive regulation of mRNA catabolic process, deadenylation-dependent
  • exact: positive regulation of mRNA catabolic process, deadenylylation-dependent
  • exact: positive regulation of mRNA catabolism, deadenylation-dependent
  • exact: positive regulation of mRNA catabolism, deadenylylation-dependent
  • exact: positive regulation of mRNA degradation, deadenylation-dependent decay
  • exact: positive regulation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • exact: up regulation of deadenylation-dependent mRNA decay
  • exact: up regulation of mRNA breakdown, deadenylation-dependent decay
  • exact: up regulation of mRNA catabolic process, deadenylation-dependent
  • exact: up regulation of mRNA catabolic process, deadenylylation-dependent
  • exact: up regulation of mRNA catabolism, deadenylation-dependent
  • exact: up regulation of mRNA catabolism, deadenylylation-dependent
  • exact: up regulation of mRNA degradation, deadenylation-dependent decay
  • exact: up regulation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • exact: up regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • exact: up-regulation of deadenylation-dependent mRNA decay
  • exact: up-regulation of mRNA breakdown, deadenylation-dependent decay
  • exact: up-regulation of mRNA catabolic process, deadenylation-dependent
  • exact: up-regulation of mRNA catabolic process, deadenylylation-dependent
  • exact: up-regulation of mRNA catabolism, deadenylation-dependent
  • exact: up-regulation of mRNA catabolism, deadenylylation-dependent
  • exact: up-regulation of mRNA degradation, deadenylation-dependent decay
  • exact: up-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • exact: up-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • exact: upregulation of deadenylation-dependent mRNA decay
  • exact: upregulation of mRNA breakdown, deadenylation-dependent decay
  • exact: upregulation of mRNA catabolic process, deadenylation-dependent
  • exact: upregulation of mRNA catabolic process, deadenylylation-dependent
  • exact: upregulation of mRNA catabolism, deadenylation-dependent
  • exact: upregulation of mRNA catabolism, deadenylylation-dependent
  • exact: upregulation of mRNA degradation, deadenylation-dependent decay
  • exact: upregulation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • exact: upregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • narrow: activation of deadenylation-dependent mRNA decay
  • narrow: activation of mRNA breakdown, deadenylation-dependent decay
  • narrow: activation of mRNA catabolic process, deadenylation-dependent
  • narrow: activation of mRNA catabolic process, deadenylylation-dependent
  • narrow: activation of mRNA catabolism, deadenylation-dependent
  • narrow: activation of mRNA catabolism, deadenylylation-dependent
  • narrow: activation of mRNA degradation, deadenylation-dependent decay
  • narrow: activation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • narrow: activation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Definition Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.