Search Unigenes:
Smed Unigene SMU15036199 : Cannot Determine

SMU15036199 is represented by 6 transcripts from 4 libraries.


Smed Unigenes are generated by clustering all available transcripts to generate a model, or Smed Unigene, representing all similar transcripts. The Smed Unigene may not accurately reflect each transcript due to biological processes such as alternative splicing.

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with ENSEMBL and SWISPROT proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms SpeciesSpecies or DBE-value
FZD5_XENLAFrizzled-5 OS=Xenopus laevis GN=fzd5 PE=2 SV=1Swissprot0.0
ENSP00000354607frizzled class receptor 5H.sapiens0.0
FBpp0074796frizzled 2H.sapiens8e-167
F27E11.3bCaenorhabditis elegans Protein CFZ-2, isoform b.H.sapiens2e-133
XP_005093188.1PREDICTED: LOW QUALITY PROTEIN: frizzled-5-like [Aplysia californica]NCBI-nr0.0
SELECTED MOTIF SIMILARITIES
Comparison of cluster transcripts with INTERPRO. The alignments can suggest function of the cluster.

Identified MotifsDatabaseMax Score
Intramembrane polypeptide regionTMHMM0.00304
Cytoplasmic polypeptide regionTMHMM0.00304
Non cytoplasmic polypeptide regionTMHMM0.00304
PF01392.17|Fz|Fz domainPFAM1.6e-31
Signal peptideSIGNALP0.673
PF01534.12|Frizzled|Frizzled/Smoothened family membrane regionPFAM1.7e-122
TRANSCRIPTS
Amino acid translations of transcipts were clustered and used to generate a Smed Unigene. These transcripts are those that were clustered as well as other transcripts and sequences that have homology to the transcripts of the unigene cluster.

Transcript IDView Assembly AlignmentsTranscript Collection
comp49556_c0_seq1
SXLWT
SMEDS2F2_00031423-RA_1_1360
UNIQ
KG_FZ-5
UNIQ
Contig54994
PN
isotig11058
BERLIN
CUFF.270995.1
BERLIN
Associated Gene Ontology Terms
Gene Ontology terms are derived from the unigene transcript cluster compared to InterPro proteins. The GO terms can suggest function of the cluster.

GO:0004930
Name G-protein coupled receptor activity
Ontology Molecular function
Synonymn
  • alt_id: GO:0001622
  • alt_id: GO:0001623
  • alt_id: GO:0001624
  • alt_id: GO:0001625
  • alt_id: GO:0016526
  • exact: G protein coupled receptor activity
  • exact: G protein linked receptor activity
  • exact: G-protein linked receptor activity
  • exact: G-protein-coupled receptor activity
  • exact: GPCR activity
  • exact: ligand-dependent GPCR activity
  • exact: receptor activity, G-protein coupled
  • narrow: EBV-induced receptor
  • narrow: Epstein-Barr Virus-induced receptor activity
  • narrow: G-protein coupled receptor activity, unknown ligand
  • narrow: Mas proto-oncogene receptor activity
  • narrow: RDC1 receptor activity
  • narrow: SREB receptor
  • narrow: orphan G protein coupled receptor activity
  • narrow: orphan G-protein coupled receptor activity
  • narrow: orphan GPCR activity
  • narrow: super conserved receptor expressed in brain receptor activity
Definition Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.

GO:0005886
Name plasma membrane
Ontology Cellular component
Synonymn
  • alt_id: GO:0005904
  • broad: juxtamembrane
  • exact: cell membrane
  • exact: cytoplasmic membrane
  • exact: plasmalemma
  • narrow: bacterial inner membrane
  • narrow: inner endospore membrane
  • narrow: plasma membrane lipid bilayer
Definition The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

GO:0016021
Name integral to membrane
Ontology Cellular component
Synonymn
  • related: transmembrane
Definition Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane.

GO:0016055
Name Wnt signaling pathway
Ontology Biological process
Synonymn
  • alt_id: GO:0007222
  • exact: Wg signaling pathway
  • exact: Wg signalling pathway
  • exact: Wingless signaling pathway
  • exact: Wingless signalling pathway
  • exact: Wnt receptor signaling pathway
  • exact: Wnt receptor signalling pathway
  • exact: frizzled signaling pathway
  • exact: frizzled signalling pathway
  • related: Wnt-activated signaling pathway
Definition The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.

GO:0042127
Name regulation of cell proliferation
Ontology Biological process
Definition Any process that modulates the frequency, rate or extent of cell proliferation.

GO:0043010
Name camera-type eye development
Ontology Biological process
Synonymn
  • alt_id: GO:0001747
  • alt_id: GO:0031075
Definition The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.

GO:0045595
Name regulation of cell differentiation
Ontology Biological process
Definition Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.

GO:0048666
Name neuron development
Ontology Biological process
Definition The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.