Search Unigenes:
Smed Unigene SMU15038936 : Cannot Determine

SMU15038936 is represented by 15 transcripts from 8 libraries.


Smed Unigenes are generated by clustering all available transcripts to generate a model, or Smed Unigene, representing all similar transcripts. The Smed Unigene may not accurately reflect each transcript due to biological processes such as alternative splicing.

SELECTED PROTEIN SIMILARITIES
Comparison of cluster transcripts with ENSEMBL and SWISPROT proteins. The alignments can suggest function of the cluster.

Best Hits and Hits from model organisms SpeciesSpecies or DBE-value
AGO2_RATProtein argonaute-2 OS=Rattus norvegicus GN=Ago2 PE=2 SV=2Swissprot0.0
FBpp0086739Argonaute-1H.sapiens0.0
F48F7.1bCaenorhabditis elegans Protein ALG-1, isoform a (alg-1) mRNA, complete cds.H.sapiens0.0
ENSP00000220592argonaute RISC catalytic component 2H.sapiens0.0
ADY05336.1AGO-2 [Schmidtea mediterranea]NCBI-nr0.0
SELECTED MOTIF SIMILARITIES
Comparison of cluster transcripts with INTERPRO. The alignments can suggest function of the cluster.

Identified MotifsDatabaseMax Score
PF08699.5|DUF1785|Domain of unknown function (DUF1785)PFAM2.9e-22
PF02171.12|Piwi|Piwi domainPFAM5.7e-111
PF02170.17|PAZ|PAZ domainPFAM3.3e-35
TRANSCRIPTS
Amino acid translations of transcipts were clustered and used to generate a Smed Unigene. These transcripts are those that were clustered as well as other transcripts and sequences that have homology to the transcripts of the unigene cluster.

Transcript IDView Assembly AlignmentsTranscript Collection
GAKN01012526.1
TORONTO
comp39177_c0_seq2
SXLWT
comp39177_c0_seq1
SXLWT
comp59180_c0_seq1
ASXLREGEN
Smed_1.0.13037
OX
Smed_1.0.06777
OX
Smed_1.0.01635
OX
smedV4_3861_0_1
DD
SMEDS2F2_00036503-RA_1_583
UNIQ
Contig35054
PN
Contig21403
PN
Contig38878
PN
Contig4179
PN
CUFF.322288.1
BERLIN
isotig13613
BERLIN
Associated Gene Ontology Terms
Gene Ontology terms are derived from the unigene transcript cluster compared to InterPro proteins. The GO terms can suggest function of the cluster.

GO:0000340
Name RNA 7-methylguanosine cap binding
Ontology Molecular function
Synonymn
  • exact: RNA m7G cap binding
Definition Interacting selectively and non-covalently with the 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.

GO:0000932
Name cytoplasmic mRNA processing body
Ontology Cellular component
Synonymn
  • exact: P body
  • exact: P-body
  • related: cytoplasmic foci
Definition A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. mRNA processing and binding proteins are localized to these foci.

GO:0005634
Name nucleus
Ontology Cellular component
Synonymn
  • exact: cell nucleus
Definition A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

GO:0005844
Name polysome
Ontology Cellular component
Synonymn
  • exact: polyribosome
Definition Several ribosomes bound to one mRNA.

GO:0005845
Name mRNA cap binding complex
Ontology Cellular component
Synonymn
  • related: mRNA cap complex
Definition Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.

GO:0006351
Name transcription, DNA-templated
Ontology Biological process
Synonymn
  • alt_id: GO:0006350
  • alt_id: GO:0061018
  • alt_id: GO:0061022
  • broad: cellular transcription
  • broad: transcription
  • exact: DNA-dependent transcription
  • exact: cellular transcription, DNA-dependent
  • exact: transcription, DNA-dependent
  • related: transcription regulator activity
Definition The cellular synthesis of RNA on a template of DNA.

GO:0006355
Name regulation of transcription, DNA-templated
Ontology Biological process
Synonymn
  • alt_id: GO:0032583
  • alt_id: GO:0045449
  • alt_id: GO:0061019
  • broad: transcriptional control
  • exact: regulation of cellular transcription, DNA-dependent
  • exact: regulation of transcription, DNA-dependent
  • related: regulation of gene-specific transcription
Definition Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

GO:0016442
Name RISC complex
Ontology Cellular component
Synonymn
  • exact: RNA-induced silencing complex
Definition A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.

GO:0030154
Name cell differentiation
Ontology Biological process
Definition The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

GO:0030529
Name ribonucleoprotein complex
Ontology Cellular component
Synonymn
  • exact: RNA-protein complex
  • exact: RNP
  • exact: protein-RNA complex
  • exact: ribonucleoprotein
Definition A macromolecular complex containing both protein and RNA molecules.

GO:0031047
Name gene silencing by RNA
Ontology Biological process
Synonymn
  • exact: RNA-mediated gene silencing
Definition Any process in which RNA molecules inactivate expression of target genes.

GO:0031054
Name pre-miRNA processing
Ontology Biological process
Synonymn
  • exact: pre-microRNA processing
Definition Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.

GO:0035068
Name micro-ribonucleoprotein complex
Ontology Cellular component
Synonymn
  • exact: miRNP complex
Definition A complex containing both protein and micro-RNA (miRNA) molecules. miRNAs are approximately 22 nucleotide noncoding RNAs derived from endogenous genes; they are processed from the stem of a longer hairpin like structure termed a pre-miRNA.

GO:0035197
Name siRNA binding
Ontology Molecular function
Synonymn
  • exact: small interfering RNA binding
Definition Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme.

GO:0035198
Name miRNA binding
Ontology Molecular function
Synonymn
  • exact: microRNA binding
Definition Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.

GO:0035278
Name negative regulation of translation involved in gene silencing by miRNA
Ontology Biological process
Synonymn
  • exact: down regulation of translation involved in gene silencing by miRNA
  • exact: down-regulation of translation involved in gene silencing by miRNA
  • exact: downregulation of translation involved in gene silencing by miRNA
  • exact: gene silencing by miRNA, negative regulation of translation
  • exact: negative regulation of translation involved in gene silencing by microRNA
  • narrow: inhibition of translation involved in gene silencing by miRNA
  • related: miRNA-mediated gene silencing, negative regulation of translation
Definition The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically repress translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs.

GO:0035279
Name mRNA cleavage involved in gene silencing by miRNA
Ontology Biological process
Synonymn
  • exact: gene silencing by miRNA, mRNA cleavage
  • exact: mRNA cleavage involved in gene silencing by microRNA
  • exact: miRNA-mediated gene silencing, mRNA cleavage
Definition The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically direct cleavage by base pairing with near-perfect complementarity to the target mRNA. Many plant miRNAs downregulate gene expression through this mechanism.

GO:0045947
Name negative regulation of translational initiation
Ontology Biological process
Synonymn
  • exact: down regulation of translational initiation
  • exact: down-regulation of translational initiation
  • exact: downregulation of translational initiation
  • narrow: inhibition of translational initiation
Definition Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.

GO:0046872
Name metal ion binding
Ontology Molecular function
Synonymn
  • exact: metal binding
  • narrow: heavy metal binding
Definition Interacting selectively and non-covalently with any metal ion.

GO:0060213
Name positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
Ontology Biological process
Synonymn
  • related: positive regulation of 3' to 5' mRNA deadenylation
  • related: positive regulation of mRNA deadenylation
  • related: positive regulation of nuclear mRNA poly(A) tail shortening
Definition Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.

GO:0070551
Name endoribonuclease activity, cleaving siRNA-paired mRNA
Ontology Molecular function
Synonymn
  • related: argonaute endoribonuclease activity
Definition Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.

GO:0090502
Name RNA phosphodiester bond hydrolysis, endonucleolytic
Ontology Biological process
Definition The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.

GO:1900153
Name positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Ontology Biological process
Synonymn
  • exact: positive regulation of deadenylation-dependent mRNA decay
  • exact: positive regulation of mRNA breakdown, deadenylation-dependent decay
  • exact: positive regulation of mRNA catabolic process, deadenylation-dependent
  • exact: positive regulation of mRNA catabolic process, deadenylylation-dependent
  • exact: positive regulation of mRNA catabolism, deadenylation-dependent
  • exact: positive regulation of mRNA catabolism, deadenylylation-dependent
  • exact: positive regulation of mRNA degradation, deadenylation-dependent decay
  • exact: positive regulation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • exact: up regulation of deadenylation-dependent mRNA decay
  • exact: up regulation of mRNA breakdown, deadenylation-dependent decay
  • exact: up regulation of mRNA catabolic process, deadenylation-dependent
  • exact: up regulation of mRNA catabolic process, deadenylylation-dependent
  • exact: up regulation of mRNA catabolism, deadenylation-dependent
  • exact: up regulation of mRNA catabolism, deadenylylation-dependent
  • exact: up regulation of mRNA degradation, deadenylation-dependent decay
  • exact: up regulation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • exact: up regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • exact: up-regulation of deadenylation-dependent mRNA decay
  • exact: up-regulation of mRNA breakdown, deadenylation-dependent decay
  • exact: up-regulation of mRNA catabolic process, deadenylation-dependent
  • exact: up-regulation of mRNA catabolic process, deadenylylation-dependent
  • exact: up-regulation of mRNA catabolism, deadenylation-dependent
  • exact: up-regulation of mRNA catabolism, deadenylylation-dependent
  • exact: up-regulation of mRNA degradation, deadenylation-dependent decay
  • exact: up-regulation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • exact: up-regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • exact: upregulation of deadenylation-dependent mRNA decay
  • exact: upregulation of mRNA breakdown, deadenylation-dependent decay
  • exact: upregulation of mRNA catabolic process, deadenylation-dependent
  • exact: upregulation of mRNA catabolic process, deadenylylation-dependent
  • exact: upregulation of mRNA catabolism, deadenylation-dependent
  • exact: upregulation of mRNA catabolism, deadenylylation-dependent
  • exact: upregulation of mRNA degradation, deadenylation-dependent decay
  • exact: upregulation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • exact: upregulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
  • narrow: activation of deadenylation-dependent mRNA decay
  • narrow: activation of mRNA breakdown, deadenylation-dependent decay
  • narrow: activation of mRNA catabolic process, deadenylation-dependent
  • narrow: activation of mRNA catabolic process, deadenylylation-dependent
  • narrow: activation of mRNA catabolism, deadenylation-dependent
  • narrow: activation of mRNA catabolism, deadenylylation-dependent
  • narrow: activation of mRNA degradation, deadenylation-dependent decay
  • narrow: activation of nuclear mRNA catabolic process, deadenylation-dependent decay
  • narrow: activation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay
Definition Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.